For centuries, explorers have risked their lives venturing into the unknown for reasons that were to varying degrees economic and nationalistic. Columbus went west to look for better trade routes to the Orient and to promote the greater glory of Spain. Lewis and Clark journeyed into the American wilderness to find out what the U.S. had acquired when it purchased Louisiana, and the Appolo astronauts rocketed to the moon in a dramatic show of technological muscle during the cold war.

Although their missions blended commercial and political-military imperatives, the explorers involved all accomplished some significant science simply by going where no scientists had gone before.

Today Mars looms（隐约出现）as humanity's next great terra incognita（未探明之地）. And with doubtful prospects for a short-term financial return, with the cold war a rapidly fading memory and amid a growing emphasis on international cooperation in large space ventures, it is clear that imperatives other than profits or nationalism will have to compel human beings to leave their tracks on the planet's reddish surface. Could it be that science, which has long played a minor role in exploration, is at last destined to take a leading role? The question naturally invites a couple of others: Are there experiments that only humans could do on Mars? Could those experiments provide insights profound enough to justify the expense of sending people across interplanetary space?